WebHSD17B13. 17β-Hydroxysteroid dehydrogenase type 13 also known as 17β-HSD type 13 is an enzyme that in humans is encoded by the HSD17B13 gene. [5] [6] 17β-HSD13 is … Web“HSD17B13” means hydroxysteroid 17-beta dehydrogenase 13 and refers to any nucleic acid of HSD17B13. For example, in certain embodiments, HSD17B13 includes a DNA …
HSD17B13 - Wikipedia
WebHSD17B13 loss-of-function mutations are protective against alcohol-related and non-alcoholic liver disease, including NASH. • ARO-HSD is a hepatocyte-targeted siRNA therapeutic designed to silence HSD17B13 expression. • ARO-HSD demonstrated a favorable safety profile in healthy volunteers and patients with suspected NASH. • Web11 nov. 2024 · Inipharm is a biopharmaceutical company focused on discovering and developing therapies for severe liver diseases. Inipharm's lead program is focused on the highly validated, genetically-defined target, HSD17B13. There is extensive, consistent evidence that genetic variants in expression of HSD17B13 are associated with … dune strawberry platform boots
Alnylam Submits CTA Application for ALN-HSD, an Investigational …
Web1 okt. 2003 · 17-beta-HSD 13 Alternative names Short chain dehydrogenase/reductase family 16C member 3 Short-chain dehydrogenase/reductase 9 Gene names Name HSD17B13 Synonyms SCDR9, SDR16C3 ORF names HMFN0376, UNQ497/PRO1014 Organism names Organism Homo sapiens (Human) Taxonomic identifier 9606 NCBI … WebHSD17B13 was shown to form homodimers in cultured cells. HSD17B13 has been reported to catalyze multiple substrates including steroids, bioactive lipids including leukotriene B4 … Web7 jan. 2024 · Recently, HSD17B13, a newly identified liver-enriched, hepatocyte-specific, lipid droplet-associated protein, has been reported to be strongly associated with the development and progression of NAFLD/NASH in both mice and humans. dune stinkhorn mushroom