Dual specificity protein phosphatase 7
WebSummary. Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. … WebProtein tyrosine phosphatase non-receptor 12 (PTPN12) is an important protein tyrosine phosphatase involved in regulating cell adhesion and migration as well as tumorigenesis. Here, we solved a crystal structure of the native PTPN12 catalytic domain with the catalytic cysteine (residue 231) in dual conformation (phosphorylated and unphosphorylated). …
Dual specificity protein phosphatase 7
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WebCell division cycle 25A (Cdc25A) is a dual-specificity phosphatase that is overexpressed in several cancer cells and promotes tumorigenesis. In normal cells, Cdc25A expression is regulated tightly, but the changes in expression patterns in cancer cells that lead to tumorigenesis are unknown. In this study, we showed that ubiquitin-specific protease 29 … WebIntroduction. Dual-specificity phosphatase 2 (DUSP2) belongs to the nuclear type I DUSP family and its molecular function is to terminate the activity of mitogen-activated protein …
WebOct 13, 2024 · Dual specificity phosphatase 7 (DUSP7) is a cytoplasmic phosphatase, which dephosphorylates extracellular signal-regulated kinases 1 and 2 (ERK1/2) . The expression of DUSP7 is upregulated, … WebPTEN is a dual-specificity phosphatase with a core promoter region and nine exons. Its full-length protein comprises 403 amino acids. PTEN has a core promoter region …
WebTo address this hypothesis, we have used genome-wide binding data to identify a relatively small set of genes that are similarly regulated by Sox10 in myelinating glia. We chose one such gene encoding Dual specificity phosphatase 15 (Dusp15) for further analysis in Schwann cell signaling. WebAug 27, 2024 · Dual-specificity phosphatases (DUSPs) are a subset of protein tyrosine phosphatases (PTPs), many of which dephosphorylate the residues of phosphor-serine/threonine and phosphor-tyrosine on mitogen-activated protein kinases (MAPKs), and hence are also referred to as MAPK phosphatases (MKPs).
WebMar 21, 2024 · DUSP7 (Dual Specificity Phosphatase 7) is a Protein Coding gene. Diseases associated with DUSP7 include Variola Major and Erythrocytosis, Familial, 7. Among its related pathways are MyD88 dependent cascade initiated on endosome and RAF/MAP …
WebDual specificity protein phosphatase (PubMed:9788880). Shows high activity towards MAPK1/ERK2 (PubMed:9788880). Also has lower activity towards MAPK14 and MAPK8 (PubMed:9788880). In arrested oocytes, plays a role in meiotic resumption (By similarity). Promotes nuclear envelope breakdown and activation of the CDK1/Cyclin-B complex in … cyrus scoffed at herWebDual specificity protein phosphatase 2 is an enzyme that in humans is encoded by the DUSP2 gene. The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. … cyrus semi flush lightWebPharos : Target Details - DUSP7 Jump to section: close Descriptive Data Protein Summary Protein Classes IDG Development Level Summary Expression Data Protein Sequence … cyrus shank 813