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Cspg4-creert2

WebOct 21, 2024 · The NG2 (cspg4)-CreERT2 knock-in mouse line had been generated previously (Huang et al., 2014). CAG-EGFP reporter mice (CMV-β actin promoter and loxP flanked CAT gene18 upstream of the EGFP cassette; Nakamura et al., 2006 ) were obtained from Leda Dimou (Ulm). WebJan 23, 2024 · The contribution of pericytes to the expansion of αSMA + vascular cells was assessed using the Cspg4-CreERTM;tdTomato flox (Cspg4-tdTomato) line, fibroblasts with the Pdgfra-CreERT2; tdTomato flox (Pdgfra-tdTomato) line, and ECs using Cdh5-CreERT2;tdTomato flox (Cdh5-tdTomato) mice (supplementary material, Figure

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Web39 recombinase driven by the pericyte-specific Cspg4 promoter (TgCspg4-CreERT2) with mice 40 carrying a Cre-responsive reporter gene (tandem dimer Tomato (tdT)) inserted at the 41 ROSA26 locus (ROSAtdT/+). The PClinmice … WebCSPG4 is a cell surface proteoglycan regulated by interleukin 11 in human endometrial epithelial cancer cells. the data suggest that CSPG4 inhibition may impair endometrial cancer progression by reducing cancer cell proliferation, migration and potentially epithelial-to-mesenchymal transition. These data suggest the possible involvement of GD3 ... i promise not to come in your mouth https://bjliveproduction.com

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WebApr 30, 2024 · For Cspg4-CreERT2/Mapt-GFP transgenic mice, tamoxifen (Sigma-Aldrich) was dissolved in corn oil (75 mg/kg) and administered s.c. 2 wk before ERβ-ligand … WebNov 17, 2024 · Pdgfrb(BAC)-CreERT2 4, 33 or B6.Cg-Tg(Cspg4-cre/Esr1*) BAkik/J (NG2-CreER TM) BAC transgenic mice 35 were interbred with Rosa26-mTmG Cre reporter mice 34 or Rosa26-YFP Cre reporter mice … WebJul 1, 2024 · CSPG4 plays a central role in the oncogenic pathways required for malignant progression and metastatization. Thanks to these features and to its poor expression in adult healthy tissues, CSPG4 represents an ideal oncoantigen and thus an attractive target for anti-tumor immunotherapy. In this review we explore the potential of CSPG4 immune ... i promise my love to you country song

Frontiers L-Type Ca2+ Channels of NG2 Glia Determine …

Category:Cspg4 Targeted Allele Detail MGI …

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Cspg4-creert2

Cspg4-CreERT2-2A - Model Org

WebJun 22, 2024 · Coexpression of NG2 and Notch3 in pulmonary pericytes is also confirmed by immunostaining in Pdgfrb-CreERT2 R26-mT/mG and Cspg4-dsRed.T1 reporter mice (Supplementary Fig. 3c, d). WebJul 6, 2024 · Cspg4 CreERT2 mice were used to label cardiac pericytes during embryonic development and is a validated model to label Cspg4 expressing cells 35 and were …

Cspg4-creert2

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WebJul 6, 2024 · Cspg4 CreERT2 mice express the tamoxifen-inducible Cre-recombinase under the control of Cspg4 promoter. Cspg4 CreERT2 mice were used to label cardiac … WebTamoxifen诱导Cre-ERT2小鼠 使用指南. Cre-ERT2在无Tamoxifen诱导的情况下，在细胞质内处于无活性状态；当Tamoxifen诱导后，Tamoxifen的代谢产物4-OHT（雌激素类似物）与ERT结合，可使Cre-ERT2进核发挥Cre重组酶活性。. 查看. 【小鼠大学问】基因工程小鼠的命名规则. 常见的 ...

WebOct 11, 2024 · CSPG4 is a cell surface proteoglycan with oncogenic functions. It recently emerged as a potential target for immunotherapy, including cell therapy based on CSPG4-specific chimeric antigen receptor (CAR)-redirected cytokine-induced killer lymphocytes (CSPG4-CAR.CIKs) in STS. However, expression of CSPG4 is poorly known in STS so far. WebThis search provides access to all the entity’s information of record with the Secretary of State. For information on ordering certificates and/or copies of documents, refer to the …

WebUpon induction, the recombination occurs in the NG2 positive cells (OPCs and pericytes). The membrane-bound GFP (mGFP) is selectively expressed in myelinating OLs, as it is … WebApr 30, 2024 · (D) Quantification analysis in EAE Cspg4-CreERT2/Mapt-GFP transgenic mice showed a significant increase in GFP mean intensity after ERβ treatment.

WebCol1a1-CreERT2 Molecular description: The transgene consists of a tamoxifen-inducible cre recombinase driven by the 2.3-kb mouse Col1a1, collagen, type I, alpha 1, promoter. The transgene insert contains a fusion product involving cre recombinase and a mutant form of the mouse estrogen receptor ligand binding domain. The mutant mouse estrogen ...

WebAug 12, 2016 · Remarkably, mural cells expressing the markers platelet-derived growth factor receptor β (PDGFRβ), CD146 and NG2/Cspg4 have been proposed to function as mesenchymal stem cells in multiple organs and act as myofibroblast progenitors during injury-induced fibrosis16,17,18. i promise just the tipWebApr 6, 2024 · It has been reported that pericytes are exclusively labeled in PDGFRβ-Flp:CSPG4-FSF-CreER mice after tamoxifen injection , highlighting the specificity of the … i promise nothingWeb2011. Age-dependent fate and lineage restriction of single NG2 cells. Zhu X , et al. PubMed: 21266410. MGI: J:167902. Development 138 (4):745-53. When using the NG2-CreER … i promise not to come in your mouth zappaWebJan 24, 2024 · NG2-CreERT2, NG2 ct2: Gene: Cspg4 Location: Chr9:56772388-56807154 bp, + strand Genetic Position: Chr9, 30.32 cM Alliance: Cspg4 tm1.1(cre/ERT2)Fki page … i promise school imagesWebNational Center for Biotechnology Information i promise school documentaryWebApr 5, 2024 · Sox9 transgenic mice combined the Cspg4-CreERT2, Rosa26 stopflox-tTA and TRE::Sox9 alleles, controls the Cspg4-CreERT2 and Rosa26 stopflox-tdTomato … i promise set it off lyricsWebCreERT2-P2A expression cassette was knocked into the Cspg4 gene . Research Application ：Cre mouse,Perivascular cell or glial cell. i promise that one day i\u0027ll be around