WebJan 26, 2015 · In cells that expressed KIF13B 442–831 tail and were treated with the linker drug, there was no change in the localization of TfR-GFP vesicles. In cells expressing KIF13B 832–1,826 tail, addition of the linker drug resulted in a pronounced redistribution of TfR-GFP to the cell center. WebApr 25, 2024 · 1) KIF13A localizes to a variety of tubular endosomes and mediates cargo recycling and transport to maturing melanosomes. 2) KIF13A forms homodimers or heterodimers with KIF13B on early/sorting endosomes and generates recycling endosomes. 3) KIF13A motor activity modulates the membrane dynamics (length and number) of …

KIF13B establishes a CAV1-enriched microdomain at the …

WebKIF13B and NPHP4 are both essential for establishment of a CAV1 membrane microdomain at the TZ, which in turn is required for Shh-induced ciliary SMO accumulation. Thus … WebAug 3, 2024 · We tested the system by expressing KIF5Cmd, which was fused to an FKBP domain and mRFP, and either KIF1Atd or KIF13Btd in cultured hippocampal neurons in two different conditions, one without rapalog and one where rapalog was added to the culture medium directly after transfection. ironbuilt steel buildings complaints

Inducible manipulation of motor–cargo interaction using …

WebApr 12, 2016 · How can both Kif13b and p38γ control Dlg1 phosphorylation, ubiquitination, and stability? ... Genotype analysis on Kif13b mutant mice was carried out on tail genomic DNA using primer pairs A plus B (415 bp floxed band and … http://bcz102.ust.hk/publications/2016/2016_Structure_An%20Atypical%20MAGUK%20GK%20Target%20Recognition%20Mode%20Revealed%20by%20the%20Interaction%20between%20DLG%20and%20KIF13B.pdf ironbuilt infrastructure pty ltd