Cisplatin alkylating agent
WebDec 19, 2011 · Alkylating agents Cause DNA cross-links and prevent cell replication ... The platinum-based chemotherapy agents cisplatin, carboplatin, and oxaliplatin, used to treat a huge number of cancers including the lung, upper and lower GI, ovarian, and germ cell tumours, are a common cause of renal tubular and glomerular damage, which can be … http://www.bccancer.bc.ca/drug-database-site/Drug%20Index/Cisplatin_monograph.pdf
Cisplatin alkylating agent
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WebAlkylating agents are effective during every phase of the life cycle of a cancer cell, which means they are effective for treating a wide range of cancers. They are most effective for treating slow-growing cancers such as leukemia and solid tumors , but are …
Cisplatin is a chemotherapy medication used to treat a number of cancers. These include testicular cancer, ovarian cancer, cervical cancer, bladder cancer, head and neck cancer, esophageal cancer, lung cancer, mesothelioma, brain tumors and neuroblastoma. It is given by injection into a vein. Common side effects include bone marrow suppression, hearing problems, incl… Webthe agent leaks outside the vein.15,17 A vesicant (Box 1) is any drug that has the potential to cause tissue damage when leakage occurs outside the vein.13 Box 1 Examples of Vesicant Chemotherapy Agents Alkylating agents: DNA binding • Nitrogen mustard Anthracyclines: DNA binding • Daunorubicin • Doxorubicin • Epirubicin • Idarubicin
WebSep 6, 2024 · Chemotherapeutic agents, also referred to as antineoplastic agents, are used to directly or indirectly inhibit the uncontrolled growth and proliferation of cancer cells. They are classified according to their mechanism of action and include. alkylating agents. , antimetabolites. , topoisomerase inhibitors. , antibiotics, mitotic inhibitors, and. WebFeb 16, 2024 · Common side effects of cisplatin may include: hearing problems; kidney problems; numbness or tingling; nausea, vomiting; or. bone marrow suppression. This is …
WebCisplatin is another alkylating agent that is used to treat lung cancer, as well as other types of cancer including testicular, ovarian, bladder, head and neck, esophageal, breast, cervical, stomach, and prostate cancers. Cisplatin is also used in the treatment of lymphomas, neuroblastoma, sarcomas, multiple myeloma, melanoma, and mesothelioma.
WebAlkylating agents Alkylating agents keep the cell from reproducing (making copies of itself) by damaging its DNA. These drugs work in all phases of the cell cycle and are used to treat many different cancers, including cancers of the lung, breast, and ovary as well as leukemia, lymphoma, Hodgkin disease, multiple myeloma, and sarcoma. csu ramweb loginWebCisplatin is classified as an alkylating agent. Alkylating agents are most active in the resting phase of the cell. These drugs are cell cycle non-specific. Note: We strongly … csu ram web log inWebDec 18, 2024 · Implications for Patient Care. Cisplatin is a platinum-based alkylating agent. It is labeled for use as a single agent for the treatment of advanced transitional cell bladder cancer, and in combination with other antineoplastic agents for the treatment of metastatic testicular cancer and metastatic ovarian cancer. [8,9,10] csu ram welcome weekWebJun 13, 2005 · Cisplatin is an antineoplastic in the class of alkylating agents and is used to treat various forms of cancer. Alkylating agents are so named because of their ability … early warning device priceWebCisplatin; Cyclophosphamide; Dacarbazine; Ifosfamide; Lomustine; Mechlorethamine; Melphalan; Oxaliplatin; Temozolomide; Thiotepa; Trabectedin; Nitrosoureas. … csu ram welcomeWeb第七章抗肿瘤药.pptx,Chapter 13 Antineoplastic Agents;Classification by mechanism; 13.1 Biological alkylating agents; Bioalkylating agents are cytotoxic drugs. In vivo, it is able to form a positive charged carbon-ion or other active electrophilic groups, and then the el early warning euWebthe agent leaks outside the vein.15,17 A vesicant (Box 1) is any drug that has the potential to cause tissue damage when leakage occurs outside the vein.13 Box 1 Examples of … early warning in construction